Chromatin Dynamics in Mammalian Development
DNA methylation is a stable epigenetic mark that is absolutely essential for proper mammalian development. In the Greenberg lab, the primary focus is understanding the various mechanisms and functions of DNA methylation in the context of development. We take a multidisciplinary approach, utilizing genetics, genomics, and biochemistry. We also strive to comprehend how DNA methylation interacts with other chromatin pathways to gain a holistic picture of chromatin-based gene regulation. For a more detailed description of our research program click here.